Close multiple tabs with shortcuts
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In pre-release it's possible to assign custom shortcuts for those commands.
Pre-release: https://www.sumatrapdfreader.org/prerelease
See https://www.sumatrapdfreader.org/docs/Customizing-keyboard-shortcuts
All commands: https://www.sumatrapdfreader.org/docs/Commands
Relevant commands: CmdCloseAllTabs, CmdCloseTabsToTheLeft, CmdCloseTabsToTheRight, CmdCloseOtherTabs